International Working Group on the Staphylococcal Cassette Chromosome elements (IWG-SCC)

SCCmec structure

  • SCCmec is defined by the characteristics listed below:
  1. It carries the class A mec gene complex, consisting of mecA, its regulatory genes, mecI and mecR1, and the insertion sequence IS431.
  2. It carries two site-specific recombinase homologues.
  3. It has characteristic direct repeats and inverted repeats at both ends.
  4. It is located at the 3’ end of orfX.

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