International Working Group on the Staphylococcal Cassette Chromosome elements (IWG-SCC)

ccr genecomplex

  • The ccr gene complex is composed of the ccr gene(s) and surrounding open reading frames (ORFs), several of which have unknown functions. Currently, three phylogenetically distinct ccr genes, ccrA, ccrB, and ccrC, have been identified in S. aureus with DNA sequence similarities below 50%.
  • Novel ccr genes should be defined based on DNA sequence similarities of <50%, and novel al- lotypes of ccr genes should be designated if their DNA sequence similarity identities are between 50% and 85%. This convention should be followed for naming novel ccr genes.

Representation of the naming conventions for ccr genes in S. aureus.

IWG-SCC commentary

Antimicrob Agents Chemother. 2009 Dec;53(12):4961-7.

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