International Working Group on the Staphylococcal Cassette Chromosome elements (IWG-SCC)

Requirement to report new SCCmec

  • SCCmec is defined by the characteristics listed below:
  1. It carries a mec gene complex, a ccr gene(s) (ccrAB and/or ccrC), its regulatory genes, such as mecI and mecR1, and the insertion sequence IS431.
  2. It carries two site-specific recombinase homologues.
  3. It has characteristic direct repeats and inverted repeats at both ends.
  4. It is located at the 3’ end of orfX.

IWG-SCC commentary Antimicrob Agents Chemother. 2009 Dec;53(12):4961-7.

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